Top articles

• Low-Dose Naltrexone for Eczema: How It May Ease Stubborn Itch

  12 avril 2026 ( #Naltrexone, #Drug, #Medication, #Eczema, #Opioid antagonist, #LDN, #Low-Dose Naltrexone, #Off-label immunomodulator, #Anti-inflammatory Agent, #Anti-pruritic, #Off-label treatment in dermatology, #Mu-opioid receptor antagonist, #Cream, #oral LDN, #Dermatology )

  Eczema, also known as atopic dermatitis, causes red, dry, and inflamed skin that often feels unbearably itchy. The itch can become so intense that people scratch until the skin breaks, leading to more inflammation, infections, and a frustrating cycle...

• Purinergic Miscommunication in Pain, Cancer, and Neurodegeneration

  21 décembre 2025 ( #purinergic signalling, #pathophysiology, #disease mechanisms, #therapeutic targets, #chronic inflammation, #neuropathic pain, #neurodegenerative diseases, #cancer immunology, #molecular pharmacology, #ATP signalling, #ATP, #adenosine signalling, #adenosine, #Health )

  When the precise language of purinergic signalling breaks down—when the volume of the conversation is turned too high, turned too low, or the messages become garbled—it can contribute to the development or progression of many diseases. Understanding this...

• Rademikibart in Asthma and Atopic Dermatitis: A Novel Biologic Targeting Type 2 Immunity

  30 mars 2026 ( #Rademikibart, #Atopic Dermatitis, #Eczema, #Type 2 Immunity, #Autoimmune Disease, #Immune System, #Immunotherapy, #immune regulation, #targeted immune therapy, #biologic, #biologic medicine, #human monoclonal antibody, #monoclonal antibody, #CBP-201 )

  Rademikibart is an experimental biologic medicine, not a traditional pill or antibiotic. It is a fully human monoclonal antibody that was originally known as CBP-201. As of March 30, 2026, it is still under clinical investigation and has not been approved...

• Differential Biological Response of Glioblastoma Multiforme Cells to Specific Extremely Low-Frequency PEMF Signals

  23 novembre 2025 ( #PEMF, #50 Hz, #100 Hz, #Cancer, #glioblastoma, #Brain, #side effect, #side effects, #Health, #Science, #grade 4 cancerous brain tumor, #cancerous brain tumor, #brain tumor, #tumor )

  Based on the study conducted by researchers at the Kerman University of Medical Sciences (referenced in the article), the effects of Pulsed Electromagnetic Fields (PEMF) on glioblastoma cells depend entirely on the specific "recipe" of frequency and magnetic...

• Anti-Inflammatory Purinergic Receptors: Mechanisms of Immune Resolution

  24 décembre 2025 ( #purinergic signaling, #Immunology, #anti-inflammatory pathways, #immune regulation, #molecular signaling pathways, #molecular signaling, #molecular signaling mechanisms, #inflammation resolution, #extracellular nucleotide signaling, #translational immunology, #therapeutic targets in inflammation, #Biology, #Science )

  Short introduction Inflammation in the body is tightly controlled by extracellular signalling systems that can either amplify immune responses or help bring them back under control once a threat has passed. One of the most important of these systems is...

• Exploring the Multifaceted Bioactivity of Heartsease (Viola tricolor): Preclinical Mechanisms and Translational Challenges

  29 mars 2026 ( #Bioactivity, #Heartsease, #Viola Tricolor, #Herbal medicine, #Herbs, #Cyclotide, #Flavonoids, #Molecule, #Science, #Flower, #anti-inflammatory, #Immunomodulator )

  Viola tricolor seems to work because it contains several different kinds of natural chemicals, and they do different jobs. The best-known ones are cyclotides, which are tiny plant peptides with a circular backbone and three disulfide bonds. That ring-shaped...

• Ibuprofen Explained: Mechanism, Benefits, Risks, and Nuances

  09 avril 2026 ( #Ibuprofen, #Analgesic, #NSAID, #Antipyretic, #anti-inflammatory, #anti-inflammatory drugs, #Anti-inflammatory Agent, #drug molecule, #organic chemical compound, #C₁₃H₁₈O₂, #Drug, #Medication )

  Ibuprofen is a molecule. It is a small organic chemical compound with the molecular formula C₁₃H₁₈O₂ and a specific three-dimensional structure. In pharmacology and chemistry, it is commonly known and referred to as a drug molecule. Ibuprofen is a common...

• Glutathione: Central Roles in Antioxidant Defense and Cellular Detoxification

  18 décembre 2025 ( #Glutathione, #Molecule, #redox, #redox agent, #redox regulator, #mitochondrial protectant, #immune-supporting compound, #intracellular defense molecule, #metabolic cofactor, #tripeptide, #cellular detoxifier )

  Glutathione is a small molecule your cells make from three amino acids (glutamate, cysteine and glycine) and it works as a central antioxidant and repair molecule inside nearly every cell. It neutralizes harmful reactive oxygen species directly, and it...

• The Alitretinoin Advantage: Dual Receptor Action, Keratinocyte Calming, and Immune Reprogramming

  02 avril 2026 ( #Alitretinoin, #9-cis-retinoic acid, #Vitamin A, #Molecule, #small organic molecule, #Organic Molecule, #Eczema, #Autoimmune Disease, #Immune System, #immune regulation, #Hand Eczema )

  Why alitretinoin can help severe chronic hand eczema Alitretinoin is a retinoid, a medicine related to vitamin A. It is used for severe chronic hand eczema that has not improved enough with strong steroid creams. It is not a general treatment for all...

• A Comprehensive Review of Regulatory T Cell Biology

  03 avril 2026 ( #Regulatory T Cells, #T Cells, #Immune System, #Autoimmune Disease, #Vitamin D, #Gut Microbiota, #Microbiology, #Microbiome, #Intestinal Microbiota, #gut bacteria, #Foxp3 )

  Regulatory T Cells: The Immune System’s Peacekeepers The immune system is designed to protect the body from germs, damaged cells, and other threats. It is a powerful defense system, but power needs control. If the immune system becomes too active, it...

• Cordyceps and Lung Health: What the Research Actually Shows

  18 avril 2026 ( #Cordyceps sinensis, #Ophiocordyceps sinensis, #Cordyceps, #Lungs, #Fungus, #Study, #Research, #medicinal mushroom, #medicinal mushrooms, #mushroom, #mushrooms )

  Cordyceps, also known as Cordyceps sinensis or Ophiocordyceps sinensis, is a fungus that has been used for centuries in traditional Chinese medicine to support respiratory health, boost energy, and ease breathing difficulties. Modern research has examined...

• LL-37: An Endogenous Antimicrobial Peptide at the Crossroads of Host Defense, Wound Repair, and Pathogen Evasion

  04 juin 2026 ( #LL-37, #LL-37 Peptide, #Peptide, #antimicrobial peptide, #Cathelicidin, #antimicrobial, #Butyrate, #Vitamin D, #Leaky Gut, #Leaky Gut Syndrome Treatment, #Leaky gut syndrome )

  Understanding LL-37: A Key Peptide in Human Health The Origin and Nature of LL-37 LL-37 is a small protein fragment, or peptide, that belongs to a family of molecules known as antimicrobial peptides. It is the only member of the cathelicidin family found...

• Spectroscopic Fingerprinting of Molecules: Theory, Measurement, and Real-World Applications

  04 août 2026 ( #Molecule, #Molecules, #Atom, #Atoms, #Electromagnetism, #Electromagnetic Fingerprint, #Electromagnetic Fingerprints, #Science, #Technology, #Spectroscopic Fingerprint, #Spectroscopic Fingerprinting of Molecules )

  THE ELECTROMAGNETIC FINGERPRINTS OF MOLECULES Every object around us, from the air we breathe to the materials in our homes, is built from molecules. These tiny structures are not frozen in place. They twist, stretch, bend, and rotate constantly. Each...

• How CBD Interacts with the Skin: Understanding Its Potential for Eczema and Psoriasis

  08 novembre 2025 ( #CBD, #Cannabidiol, #Eczema, #Psoriasis, #Skin, #Science, #Health, #Cannabis, #Herbal medicine, #Herbs )

  CBD is a natural compound from the cannabis plant that helps calm the body and reduce inflammation without making you feel high. Cannabidiol (CBD) shows real potential to help with inflamed, scaly, itchy skin (the hallmarks of eczema and psoriasis) because...

• Therapeutic Uses and Benefits of Corticosteroids

  29 décembre 2025 ( #Corticosteroid, #steroid hormones, #anti-inflammatory drugs, #immunosuppressive agents, #glucocorticoid hormones, #steroid medications, #endocrine therapies, #prescription pharmaceuticals, #Drug, #Medication )

  Corticosteroids are a family of medicines that copy the action of hormones your body makes in the adrenal glands (small glands that sit above your kidneys). In plain terms, they tell the immune system and body tissues to “calm down” when there is inflammation...

• The Microbial Dimension of Atopic Dermatitis: Historical Perspectives and Emerging Therapeutic Implications

  22 février 2026 ( #Eczema, #Pathogen, #Microorganism, #Microbes, #Staphylococcus aureus, #Skin Condition, #Skin Biology, #Bacteria, #Staphylococci, #History of Medicine )

  Eczema (atopic dermatitis) is best understood today as a condition where three things meet and feed each other: an imperfect skin barrier, an over-reactive immune system, and changes in the microbes that live on the skin. The idea that bacteria play a...

• Butyrate and Colonic Homeostasis: The Short-Chain Fatty Acid Link Between Dietary Fiber and Epithelial Integrity.

  24 novembre 2025 ( #Butyrate, #Chemical Compound, #Gastroenterology, #Nutritional Science, #Leaky Gut, #Leaky gut syndrome, #Health, #Science, #Food, #Food-Science )

  Butyrate is a short-chain fatty acid that serves as the primary fuel source for the cells lining your colon. You can think of it as a form of energy that your body does not make on its own; instead, it is created by the friendly bacteria living in your...

• " My personal microplastics protocol " by Robin Berzin

  22 janvier 2026 ( #microplastic, #Pollution, #Health, #Robin Berzin, #Detox, #Leaky Gut, #Leaky gut syndrome, #PEMF, #Technology, #Sulforaphane )

  This week I got a lot of “THIS IS REALLY SCARY” messages from patients and friends after a recent study linked phthalates in plastic food containers to over 13% of all global heart disease deaths in 2018. It seems like each week brings a new microplastics...

• Tilrekimig : a new trispecific antibody shows promise in treating eczema

  30 mars 2026 ( #Tilrekimig, #Eczema, #trispecific antibody, #Drug, #Medication, #Pfizer, #trispecific monoclonal antibody, #PF-07275315, #Anti-inflammatories, #Immunomodulator )

  Pfizer’s trispecific antibody shows promise in treating eczema : The pharmaceutical giant announced its candidate, tilrekimig, significantly reduced eczema severity in clinical trials. Pharmaceutical conglomerate Pfizer recently announced promising Phase...

• Rapamycin Under the Microscope: Benefits, Risks, and Unresolved Questions

  06 avril 2026 ( #Rapamycin, #Sirolimus, #Immunomodulator, #Immunomodulation, #complex natural macrolide compound, #molecule, #organic molecule, #anti aging, #Drug, #Medication )

  Rapamycin: What It Is and Why It Matters Rapamycin is a medicine that is also called sirolimus, and one common brand name is Rapamune. In the United States, it was first approved in 1999. Its main approved use is to help prevent organ rejection after...

• Interleukins: The Immune System's Dynamic Communication Network

  01 avril 2026 ( #Interleukins, #Interleukin, #Molecule, #Immune System, #Cytokines, #Cytokine, #cell signaling, #Immune Messengers, #Microbiology, #IL )

  What Are Interleukins? Interleukins are tiny messenger proteins used by the immune system. Their job is to help immune cells talk to each other. The word itself gives a clue: “inter” means between, and “leukin” refers to white blood cells. So interleukins...

• Understanding Cordyceps: A Plain Language Guide to Its Health Effects

  18 avril 2026 ( #Cordyceps, #Funfus, #Cordyceps sinensis, #Ophiocordyceps sinensis, #Cordyceps militaris, #Cs-4, #medicinal mushroom, #medicinal mushrooms, #mushroom, #mushrooms )

  Cordyceps is a fungus that has captured the attention of both traditional healers and modern scientists. This mushroom, which famously grows by infecting and consuming the larvae of certain insects, has been a cornerstone of traditional Chinese and Tibetan...

• Beta-Glucan and Health: What It Does, What It Does Not Do

  25 avril 2026 ( #Beta-Glucan, #β-glucan, #β-glucans, #Beta-glucans, #Dietary fiber, #polysaccharide molecule, #Molecule, #Science, #Health, #Gut Health )

  Beta-glucan is a type of soluble fiber found most famously in oats and barley, and also in yeast and mushrooms. In foods, it acts differently from ordinary starch and sugar because it is not digested in the same way. Cereal beta-glucan, especially from...

• The Multifaceted Contribution of Vitamin B6 to Dermatological Health: Ceramides, Prostaglandins, and Pellagra-Like Dermatitis

  03 juin 2026 ( #Vitamin B6, #Vitamin, #Skin Biology, #Skin, #Skin Health, #Cutaneous Health, #GLA, #gamma-linolenic acid, #Dermatological Health, #Dermatology )

  Key Takeaways: Vitamin B6 is essential for converting tryptophan into niacin (B3); low B6 can cause niacin deficiency skin rashes even if you eat enough niacin. B6 supports ceramide production, strengthening the skin barrier and reducing dryness/sensitivity....

• Apigenin and Cellular Energy: The Metabolic Spark

  11 juin 2026 ( #Apigenin, #Flavonoid, #Mitochondria, #Mitochondrial Biology, #Mitochondrial Biogenesis, #Calorie-Burning Partner, #Cell Metabolism, #Cell Biology, #Cells, #cellular energy metabolism )

  An Unexpected Influence on Mitochondria The tiny energy factories within cells, known as mitochondria, do far more than simply produce fuel. They govern metabolism, signal cellular health, and decide whether a cell lives or dies. Recent research has turned...