Top articles

• Butyrate and Epithelial Integrity: Clarifying the Biological Mechanisms

  25 novembre 2025 ( #Butyrate, #Gastroenterology, #Chemical Compound, #Leaky Gut, #Leaky gut syndrome, #Science, #Health, #Gut )

  Butyrate tightens the gut barrier through several complementary, fairly direct actions on the cells that line the intestine and on the local immune signals around them. First, colon cells use butyrate as a preferred fuel: when those cells burn butyrate...

• L-Glutamine: Physiological Functions and Evidence-Based Benefits

  29 novembre 2025 ( #L-Glutamine, #Chemical Compound, #Molecule, #Gut, #Leaky Gut, #Leaky gut syndrome, #Science, #Health )

  L-glutamine is an amino acid your body normally makes, but during stress, illness, or heavy training your tissues can use more than your body can produce — so it becomes “conditionally essential.” Explaining what it does and why people take it becomes...

• Understanding Retrogradation: How Cooked Starch Reorganizes as It Cools

  29 novembre 2025 ( #Retrogradation, #Biochemistry, #Food-Science, #Food, #Starch, #Chemistry, #Gut Health, #Butyrate )

  Retrogradation is a simple, everyday change that happens to cooked starchy foods as they cool: the loose, swollen starch molecules (C6H10O5)n that formed when you cooked the food slowly re-align and stick back together, making the texture firmer or drier....

• Introduction to Zinc Carnosine and Digestive Health

  02 décembre 2025 ( #Zinc Carnosine, #Chemical Compound, #Zinc, #Molecule, #Nutritional supplement, #Gastroprotective agent, #Zinc L-carnosine, #Gastroenterology )

  Zinc carnosine (also called polaprezinc) is a simple supplement made from the mineral zinc joined to a small molecule called carnosine. In plain terms, it’s used to help protect and heal the soft lining of the stomach and the rest of the gut. When people...

• How Retinoids Normalize Skin Cell Behavior in Psoriasis

  11 décembre 2025 ( #Retinol, #Psoriasis, #Dermatology, #Skin Biology, #Biology, #Skin, #Science, #Health )

  Psoriasis is a disorder in which the skin’s normal cycle of cell growth and maturation is thrown off: skin cells called keratinocytes divide too quickly and fail to mature normally, producing thick, scaly plaques. Retinoids—drugs chemically related to...

• Inositol Hexaphosphate (IP6): Current Evidence on Biological Activity and Safety

  17 décembre 2025 ( #Inositol Hexaphosphate, #IP6, #Molecule, #dietary compound, #bioactive phytochemical, #plant-derived molecule, #antioxidant agent, #nutraceutical )

  Inositol hexaphosphate (IP6), also called phytic acid or “phytate” when in salt form, is a naturally occurring compound found mainly in bran, seeds, legumes and other high-fiber plant foods. In the body it acts as a multitasker: chemically it’s a strong...

• Spermidine Biosynthesis in the Human Intestine: The Role of Commensal Bacteria

  18 décembre 2025 ( #Spermidine, #Molecule, #microbiome, #gut bacteria, #polyamines, #nutritional biochemistry, #microbial metabolism, #molecular nutrition )

  Spermidine is a small organic molecule called a polyamine that cells use for growth, repair and many basic processes. In the human gut it comes from three places: the food we eat, the cells of our own body, and the bacteria that live in the intestine....

• Purinergic Pathways in Immune Activation and Autoimmune Pathology

  22 décembre 2025 ( #purinergic signalling, #Purinergic Pathway, #Autoimmune Disease, #Immune System, #Biology, #immune regulation, #molecular signaling pathways, #inflammation biology )

  Purinergic signalling is the cell-to-cell communication system that uses simple purine molecules—mainly extracellular ATP (adenosine triphosphate) and its breakdown product adenosine—to shape immune behaviour. Cells release ATP when they are stressed,...

• Barrier Repair: Why Ceramide Creams Matter

  27 décembre 2025 ( #Lipid, #Lipids, #Ceramide, #Cream, #Eczema, #Psoriasis, #Skin, #Skin Biology )

  Ceramide-containing regimens are simply skin-care plans that use products formulated with ceramides — the natural fats your skin needs to build a strong outer barrier — together with other lipids that the skin normally makes. Ceramides are one of the...

• Why Diet Matters for Inflamed Skin — and Why It’s Not the Whole Answer

  27 décembre 2025 ( #Diet, #Food, #dietary compound, #Food-Science, #Eczema, #Psoriasis, #Lipid, #Lipids )

  Short answer: some foods contain the kinds of fats and building blocks that help skin make healthy lipids, and eating a balanced diet that includes those foods can support skin health — but eating foods alone is not a quick substitute for topical barrier...

• Understanding the Biology of Topical Steroid Withdrawal

  29 décembre 2025 ( #Corticosteroid, #Steroid, #steroid medications, #Steroid Cream, #Cream, #Dermatology, #side effect, #side effects )

  Topical steroid withdrawal happens when skin that has been exposed to regular, often high-potency steroid creams for weeks to months reacts badly after the medicine is stopped. Instead of simply returning to the baseline rash, the skin can turn intensely...

• From Salt to Symptom Picture: A Historical Analysis of Natrum Muriaticum in the Homeopathic Materia Medica

  16 janvier 2026 ( #Natrum Muriaticum, #Homeopathy, #Natrium Chloratum, #Table Salt, #Salt, #Sodium Chloride, #History, #History of Medicine )

  Natrium chloratum — better known in homeopathic literature by its classical name Natrum muriaticum — has a history that runs almost as far back as homeopathy itself. The remedy’s source material is ordinary sodium chloride (common salt), and it entered...

• Rapamycin and the Hallmarks of Aging: A Mechanistic Review

  07 avril 2026 ( #Rapamycin, #rapamycin, #anti aging, #Anti-Aging, #Drug, #Medication, #Immunomodulation, #Immunomodulator )

  Rapamycin and the Science of Slowing Aging Rapamycin is a compound first discovered in the soil of a remote Pacific island. Doctors originally used it to prevent organ rejection after transplants because it calms the immune system. In recent decades,...

• Huang Qi: The Yellow Leader in the Materia Medica of Traditional Chinese Medicine

  11 avril 2026 ( #Huang Qi, #Astragalus Root, #Astragalus, #Chinese herbology, #Herbal medicine, #TCM, #traditional chinese medicine, #Traditional Medicine )

  Introduction In the vast pharmacopoeia of Traditional Chinese Medicine (TCM), few herbal substances command the reverence and widespread application accorded to Huang Qi, known in the West as Astragalus. Derived from the dried root of Astragalus membranaceus...

• Reishi (Lingzhi): What the Science Really Says About This Traditional Mushroom

  13 avril 2026 ( #Ganoderma lucidum, #Reishi, #lingzhi, #medicinal mushrooms, #mushroom, #medicinal mushroom, #fungus, #woody fungus )

  Reishi (Ganoderma lucidum): What It Is and What It Does Reishi, also called Ganoderma lucidum or lingzhi, is a mushroom that has been used for centuries in traditional East Asian medicine. It is sold today as capsules, tablets, extracts, powders, and...

• Cordyceps in Medicine: Molecular Constituents, Potential Benefits, and Research Limits

  18 avril 2026 ( #Cordyceps, #Fungus, #mushroom, #mushrooms, #medicinal mushroom, #medicinal mushrooms, #Cordyceps sinensis, #Cordyceps militaris )

  Cordyceps and Health: What the Evidence Says Cordyceps is a type of fungus used in traditional Chinese medicine. It is sold as capsules, powders, and liquid extracts, and it is often marketed for energy, stamina, immune support, kidney health, and general...

• Chaga Mushroom Update 2025–2026: Human Data, Neuroprotection, and a New Adulteration Warning

  23 avril 2026 ( #Chaga, #Fungus, #medicinal mushroom, #Inonotus Obliquus, #Akkermansia Muciniphila, #Gut Microbiota, #Intestinal Microbiota, #microbiome )

  There are a few additional nuances and emerging areas of research that can further round out the understanding of Chaga's effects on health without repeating the core content already provided. One important detail involves the method of extraction. The...

• Not All Beta-Glucans Are Created Equal: Structure, Source, and Immune Function

  25 avril 2026 ( #Beta-glucans, #Beta-Glucan, #Immune Function, #Immune System, #Immunomodulator, #Immunomodulation, #polysaccharide molecule, #Molecule )

  Understanding Beta-Glucans and Their Complex Relationship with the Immune System Beta-glucans are a group of naturally occurring complex sugars, or polysaccharides, found within the cell walls of organisms as diverse as yeast, mushrooms, barley, and oats....

• Understanding Phosphatidylcholine: A Vital Nutrient for Health

  18 mai 2026 ( #Phosphatidylcholine, #fat molecule, #phospholipid, #phospholipids, #lecithin, #component of biological membranes, #Molecule, #phospholipid molecule )

  What Is Phosphatidylcholine? Phosphatidylcholine is a type of fat molecule that belongs to a group of compounds called phospholipids. It is one of the most abundant phospholipids in the cells of plants, animals, and humans. Structurally, it consists of...

• Boswellia and the Skin: How an Ancient Resin Speaks to Eczema and Inflammation

  26 avril 2026 ( #Boswellia, #Eczema, #Herbal medicine, #Herbs, #Skin Condition, #Psoriasis, #Health, #Medicine )

  Introduction The sticky golden resin from the Boswellia tree has traveled through history as frankincense, a gift for kings and a fragrant offering in sacred spaces. Yet its modern promise lies not in its smoke but in its chemistry. For the millions of...

• Urea in Human Health and Disease: From Metabolic Waste to Therapeutic Agent and Pathogenic Mediator

  27 mai 2026 ( #Urea, #CO(NH₂)₂, #Organic Compound, #Amide (diamide), #Nitrogenous waste product, #Small polar molecule, #Keratolytic agent, #Molecule )

  Understanding Urea and Its Effects on Health What Urea Is and Where It Comes From Urea is a natural substance made by the body every day. It forms in the liver when the body breaks down protein from food. After proteins are digested, their building blocks,...

• LL-37 and Eczema: Why the Picture Is Mixed

  04 juin 2026 ( #LL-37, #LL-37 Peptide, #Peptide, #Eczema, #Skin Health, #Skin, #Skin Biology, #pruritic skin disease )

  LL-37 is a natural antimicrobial peptide found in the skin. It helps the body defend against germs and also affects how skin cells behave. In laboratory and review studies, LL-37 has shown both helpful and harmful effects on skin inflammation, which is...

• Hidden Protections: Apigenin and Organ-Specific Resilience

  10 juin 2026 ( #Apigenin, #Detoxification Support, #Detox, #Pain Management, #Hair Growth, #Skin Wound Healing, #Flavonoids, #Flavonoid )

  Liver Health and Detoxification Support The liver, as the body’s main detoxification hub, appears to benefit significantly from apigenin. In animal models and cell studies, apigenin has been shown to shield liver cells from damage caused by alcohol, industrial...

• The Dual Role of Urocanic Acid in Skin Biology: Photoprotection, Immune Regulation, and Disease

  25 juin 2026 ( #Urocanic Acid, #Skin, #Skin Biology, #Skin Health, #Histidine, #Metabolite, #Skin Cancer, #Cancer )

  Cis-urocanic acid (the form produced when UV light hits trans-urocanic acid in the skin) suppresses local skin immunity by: - Dampening T-cell responses - Promoting immune tolerance to antigens - Activating the serotonin receptor (5-HT2A) on immune cells...

• Dupilumab or JAK Inhibitors? Choosing the “Best” Modern Treatment for Eczema

  29 décembre 2025 ( #Eczema, #Drug, #Medication, #Dupilumab, #JAK Inhibitors, #Treatment for Eczema, #Modern Treatment for Eczema, #Eczema Treatment )

  There isn’t a one-size-fits-all “best” drug — but for most people the safest, most broadly useful single choice is usually dupilumab; if you (or your doctor) need the fastest and largest skin improvement and you are otherwise at low cardiovascular/infection...