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US Doctors warn that seed oils could cause colon cancer

14 Décembre 2024, 20:39pm

Publié par Box News

US Doctors warn that seed oils could cause colon cancer

A new Government-funded study has suggested that common cooking oils used by millions could be contributing to a worrying surge in colon cancer cases among young people. Research published in the journal Gut has found that seed oils - including sunflower, canola, corn and grapeseed varieties - may be fuelling one of the fastest-growing forms of the disease. The groundbreaking study, conducted by researchers at the University of South Florida, analysed tumour samples from more than 80 cancer patients.

Scientists discovered high levels of bioactive lipids, which are microscopic fatty compounds produced when the body breaks down seed oils, in the samples. Seed oils have become increasingly prevalent in modern diets, with the average person consuming nearly 100 pounds annually - a thousand-fold increase since the 1950s.  The research team examined 81 tumour samples from colorectal cancer patients aged between 30 and 85 years old and more than half of the studied patients had advanced stage three or four cancer.
Scientists found significantly higher concentrations of bioactive lipids compared to healthier fats within the tumours.

The study has suggested that these oils may be particularly problematic due to their high omega-6 fatty acid content. Researchers explained that these oils can be dangerous in two distinct ways: first, they promote inflammation which helps cancers grow and develop and, secondly, they prevent the body's natural defences from fighting the tumours effectively. The inflammation process causes cells to constantly split and regenerate in the colon, making them more susceptible to cancer-causing mutations. Chronic inflammation also weakens the immune system's ability to destroy abnormal cells. The study has noted that when seed oils are consumed, they undergo a complex biochemical process, forming compounds called eicosanoids - a type of bioactive lipid that has been linked to inflammation in the colon. Dr Timothy Yeatman, study author and professor of surgery at USF Health Morsani College of Medicine, said: "It is well known that patients with unhealthy diets have increased inflammation in their bodies." 

The American study has followed President-elect Donald Trump's appointment of Robert F Kennedy Jr as health secretary, who has said that Americans are "unknowingly poisoned by them", referring to the oils. "We now see this inflammation in the colon tumours themselves, and cancer is like a chronic wound that won't heal."  The researchers have recommended switching to healthier alternatives like olive and avocado oil, as Yeatman added: "This has the potential to revolutionise cancer treatment, moving beyond drugs to harness natural healing processes." "It's a vital step toward addressing chronic inflammation and preventing diseases before they start." The findings come amid alarming projections for colon cancer rates among young people, while experts have started to predict diagnoses among people under 50 years old will rise dramatically by 2030. Specifically, cases in people aged 20 to 34 are expected to increase by 90 per cent compared to 2010 levels. While no single cause has been definitively identified, ultra-processed foods are believed to be a significant factor, which typically contain fats, sugars and other chemicals that contribute to inflammation in the digestive tract.

(Source : GBNews)

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PEMF : Inhibition of tumor cell or tissue proliferation

27 Février 2024, 23:49pm

Publié par Box News

PEMF : Inhibition of tumor cell or tissue proliferation

Abstract

Cancer is one of the major diseases that endanger human health. Current treatment options have low patient tolerance, poor prognosis, and strong side effects. Pulsed electromagnetic therapy can selectively kill cancer cells by taking advantage of their own electromagnetic sensitivity specificity. Pulsed electric fields (PEFs), pulsed electromagnetic fields (PEMFs), and cold atmospheric plasma (CAP) are three main means that have promising application in cancer therapy. Pulsed electromagnetic therapy showed significant anticancer ability in vitro and in vivo. In this paper, we summarize the basic principles, methods, and state of art research of PEFs, PEMFs, and PEMFs for cancer therapy. Based on cancer pro-oxidation therapy, we propose a combination therapy of electromagnetic field-enhanced CAP for cancer therapy.

Inhibition of tumor cell or tissue proliferation

Zeng et al. found that tumor growth in mice was inhibited by the effect of 0.6–2.0 T magnetic field. The metabolism, mitosis, and high-speed anomalous growth of tumor cells were inhibited in the irradiated group. de Seze et al. applied a magnetic field with an intensity of 0.12 T and a frequency of 0.8 Hz to natural killer cells and observed a significant increase in the proliferation of natural killer cells within 1 week compared to the previous one, indicating that a magnetic field of this intensity can improve the body's ability to suppress cancer. Tuffet and de Seze found that 0.18 T, 0.8 Hz unipolar square wave pulsed magnetic field reduced the proliferation of isolated cervical cancer cells by 15%. Under the same parameters, pulsed magnetic field treatment for 8 h a day, 5 days a week, significantly prolonged the survival of tumor-bearing mice. The effect of the nonuniform field was better than that of the uniform field, with the pulsed magnetic field producing the highest induced current at the edge of the subject and the lowest induced current at the center. Cameron et al. used a pulsed magnetic field (15 mT, 120 pulses/s) to treat human breast cancer cells (MDA-MB-231) transplanted into mice. It was found that the growth of breast cancer was effectively inhibited in the irradiated mice compared to the nonmagnetic field irradiated mice, while the tumors in the original lung metastases in the mice were significantly reduced, with slow tumor growth and no significant harmful side effects. Filipovic et al. investigated the effects of a 50 Hz magnetic field on different types of cancer cells. Breast cancer cells MDA-MB-231, colorectal cancer cells SW-480, and HCT-116 were irradiated under a specific magnetic field for 24–72 h, and the results showed that the growth of all three types of cancer cells was significantly inhibited. Williams et al.61 further found that 10 min of daily 10, 15 or 20 mT pulsed magnetic field irradiation (120 pulses/s) significantly slowed tumor growth and reduced vascularization relative to mice not exposed to magnetic fields.

(Source : OnlineLibrayWiley)

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